When I was at the Dallas Motrocycle Show a few weeks ago I was with a few guys who seemed very knowledgable about the on/off road market. Anyways, I guess the new Yamaha ON/OFF roads use titanium valves and there is a problem with them wearing prematuraly and require frequent adjustments. From what I understood from the guy is that almost everyone ends up swapping them out for stainless valves. In the end they are cheaper, last longer, and require less adjustments. All outweighing the potential performance/costs from titatinium valves.
Now again this is regarding off road only so we are talking much higher RPM's. I have no knowledge on the subject on VTWIN, but I suspect much of the same result. Maybe John Sachs can chim in on his experience.